| Gene Information | |
|---|---|
| Gene Name | KLC1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 573 |
| Protein Names | Kinesin light chain 1 (KLC 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000126214 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q07866 |
| Gene Card | KLC1 |
| Uniprot ID | Q07866 |
| Pfam | PF13176 |
| In ASD | no |
| Allosteric Prediction | yes (0.02452148) |
| Ortholog in Animals | Alpaca_ KLC1 ( ortholog_one2one ) Dog_ KLC1 ( ortholog_one2one ) GuineaPig_ KLC1 ( ortholog_one2one ) Macaque_ KLC1 ( ortholog_one2one ) Mouse_ Klc1 ( ortholog_one2one ) Pig_ KLC1 ( ortholog_one2one ) Rat_ Klc1 ( ortholog_one2one ) Rabbit_ KLC1 ( ortholog_one2one ) |
| Ohnologs | KLC4, KLC2 |
| Paralogs | KLC2, APPBP2, KLC3, NPHP3, KLC4 |
| Tissue | NA |
| Tissue Specificity | Found in a variety of tissues. Mostly abundant in brain and spine. {ECO:0000269|PubMed:14970196}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3NF1 (X-ray 2.80A ) 5OJ8 (X-ray 2.25A ) 7AI4 (X-ray 2.79A ) 7AIE (X-ray 3.29A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cell projection, growth cone {ECO:0000250}. Cytoplasmic vesicle {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000305|PubMed:14970196}. |
| Mouse PG classification | NA |
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