| Gene Information | |
|---|---|
| Gene Name | ATG3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 314 |
| Protein Names | Ubiquitin-like-conjugating enzyme ATG3 (EC 2.3.2.-) (Autophagy-related protein 3) (APG3-like) (hApg3) (Protein PC3-96) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000144848 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9NT62 |
| Gene Card | ATG3 |
| Uniprot ID | Q9NT62 |
| Pfam | PF03987 |
| In ASD | yes |
| Allosteric Prediction | no (-1.000334724) |
| Ortholog in Animals | Alpaca_ ATG3 ( ortholog_one2one ) Dog_ ATG3 ( ortholog_one2one ) GuineaPig_ ATG3 ( ortholog_one2one ) Macaque_ ATG3 ( ortholog_one2one ) Mouse_ Atg3 ( ortholog_one2one ) Pig_ ATG3 ( ortholog_one2one ) Rat_ Atg3 ( ortholog_one2one ) Rabbit_ ATG3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed, with a highest expression in heart, skeletal muscle, kidney, liver and placenta. {ECO:0000269|PubMed:11825910}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.024(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4NAW (X-ray 2.20A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:11825910}. |
| Mouse PG classification | NA |
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