Gene Information | |
---|---|
Gene Name | KIRREL3 |
Organism | Homo sapiens (Human) |
Gene Length | 778 |
Protein Names | Kin of IRRE-like protein 3 (Kin of irregular chiasm-like protein 3) (Nephrin-like protein 2) [Cleaved into: Processed kin of IRRE-like protein 3] |
Target Name | NA |
Target Type | NA |
Gene Age | 680 ( ENSG00000149571 ) |
Evolutionary Stage | Vertebrata |
AlphaFoldDB | Q8IZU9 |
Gene Card | KIRREL3 |
Uniprot ID | Q8IZU9 |
Pfam | PF07679; PF13895 |
In ASD | no |
Allosteric Prediction | no (-0.540765989) |
Ortholog in Animals | Alpaca_ KIRREL3 ( ortholog_one2one ) Dog_ KIRREL3 ( ortholog_one2one ) GuineaPig_ KIRREL3 ( ortholog_one2one ) Macaque_ KIRREL3 ( ortholog_one2one ) Mouse_ Kirrel3 ( ortholog_one2one ) Pig_ KIRREL3 ( ortholog_one2one ) Rat_ Kirrel3 ( ortholog_one2one ) Rabbit_ KIRREL3 ( ortholog_one2one ) |
Ohnologs | KIRREL2, KIRREL1 |
Paralogs | KIRREL2, NPHS1, KIRREL1 |
Tissue | brain |
Tissue Specificity | Expressed in fetal and adult brain (PubMed:19012874). Also expressed in kidney, specifically in podocytes of kidney glomeruli (PubMed:12424224). Also expressed in skeletal muscle (PubMed:25488023). {ECO:0000269|PubMed:12424224, ECO:0000269|PubMed:19012874, ECO:0000269|PubMed:25488023}. |
Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.2(Rabbit) |
Gene Ontology (biological process) |
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Gene Ontology (cellular component) |
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Gene Ontology (molecular function) |
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PDB | 2CRY (NMR - ) |
DBSNP | rs119462978 rs114378922 rs119462980 |
Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:19012874}; Single-pass type I membrane protein {ECO:0000269|PubMed:19012874}.; [Processed kin of IRRE-like protein 3]: Secreted {ECO:0000250|UniProtKB:Q8BR86}. |
Mouse PG classification | NA |
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