| Gene Information | |
|---|---|
| Gene Name | CERT1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 624 |
| Protein Names | Ceramide transfer protein (hCERT) (Collagen type IV alpha-3-binding protein) (Goodpasture antigen-binding protein) (GPBP) (START domain-containing protein 11) (StARD11) (StAR-related lipid transfer protein 11) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000113163 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q9Y5P4 |
| Gene Card | CERT1 |
| Uniprot ID | Q9Y5P4 |
| Pfam | PF00169; PF01852 |
| In ASD | no |
| Allosteric Prediction | no (-0.181359869) |
| Ortholog in Animals | Alpaca_ CERT1 ( ortholog_one2one ) Dog_ CERT1 ( ortholog_one2one ) GuineaPig_ CERT1 ( ortholog_one2one ) Macaque_ CERT1 ( ortholog_one2one ) Mouse_ Cert1 ( ortholog_one2one ) Pig_ CERT1 ( ortholog_one2one ) Rat_ Cert1 ( ortholog_one2one ) Rabbit_ CERT1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CPTP, GLTPD2, PLEKHA8, GLTP, PLEKHA3 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2E3M (X-ray 2.20A ) 2E3N (X-ray 1.40A ) 2E3O (X-ray 1.55A ) 2E3P (X-ray 1.40A ) 2E3Q (X-ray 2.08A ) 2E3R (X-ray 1.65A ) 2E3S (X-ray 1.94A ) 2RSG (NMR - ) 2Z9Y (X-ray 1.80A ) 2Z9Z (X-ray 1.74A ) 3H3Q (X-ray 2.00A ) 3H3R (X-ray 1.85A ) 3H3S (X-ray 1.66A ) 3H3T (X-ray 2.40A ) 4HHV (X-ray 1.75A ) 5JJD (X-ray 2.40A ) 5ZYG (X-ray 1.80A ) 5ZYH (X-ray 1.95A ) 5ZYI (X-ray 1.90A ) 5ZYJ (X-ray 1.90A ) 5ZYK (X-ray 1.55A ) 5ZYL (X-ray 1.80A ) 5ZYM (X-ray 1.90A ) 6IEZ (X-ray 1.90A ) 6IF0 (X-ray 1.80A ) 6J0O (X-ray 1.80A ) 6J81 (X-ray 1.80A ) |
| DBSNP | rs1064794019 rs55882089 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:16895911, ECO:0000269|PubMed:18184806}. Golgi apparatus {ECO:0000269|PubMed:16895911, ECO:0000269|PubMed:18184806, ECO:0000269|PubMed:29858488}. Endoplasmic reticulum {ECO:0000269|PubMed:16895911, ECO:0000269|PubMed:18184806}. Note=Preferentially localized to the Golgi apparatus. {ECO:0000305|PubMed:16895911}. |
| Mouse PG classification | NA |
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