| Gene Information | |
|---|---|
| Gene Name | KIR3DL2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 455 |
| Protein Names | Killer cell immunoglobulin-like receptor 3DL2 (CD158 antigen-like family member K) (Natural killer-associated transcript 4) (NKAT-4) (p70 natural killer cell receptor clone CL-5) (p70 NK receptor CL-5) (CD antigen CD158k) |
| Target Name | mhc class i nk cell receptor 3dl2 |
| Target Type | Clinical trial target |
| Gene Age | 3 ( ENSG00000240403 ) 3 ( ENSG00000273735 ) 3 ( ENSG00000273911 ) 3 ( ENSG00000274722 ) 3 ( ENSG00000275083 ) 3 ( ENSG00000275262 ) 3 ( ENSG00000275416 ) 3 ( ENSG00000275511 ) 3 ( ENSG00000275566 ) 3 ( ENSG00000275626 ) 3 ( ENSG00000275629 ) 3 ( ENSG00000275838 ) 3 ( ENSG00000276004 ) 3 ( ENSG00000276357 ) 3 ( ENSG00000276424 ) 3 ( ENSG00000276739 ) 3 ( ENSG00000276882 ) 3 ( ENSG00000277181 ) 3 ( ENSG00000277709 ) 3 ( ENSG00000277982 ) 3 ( ENSG00000278361 ) 3 ( ENSG00000278403 ) 3 ( ENSG00000278442 ) 3 ( ENSG00000278474 ) 3 ( ENSG00000278656 ) 3 ( ENSG00000278707 ) 3 ( ENSG00000278710 ) 3 ( ENSG00000278726 ) 3 ( ENSG00000278758 ) 3 ( ENSG00000278809 ) 3 ( ENSG00000278850 ) 3 ( ENSG00000283951 ) 3 ( ENSG00000283975 ) 3 ( ENSG00000284046 ) 3 ( ENSG00000284063 ) 3 ( ENSG00000284192 ) 3 ( ENSG00000284213 ) 3 ( ENSG00000284295 ) 3 ( ENSG00000284381 ) 3 ( ENSG00000284384 ) 3 ( ENSG00000284466 ) 3 ( ENSG00000284528 ) 3 ( ENSG00000288389 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | P43630 |
| Gene Card | KIR3DL2 |
| Uniprot ID | P43630 |
| Pfam | PF00047 |
| In ASD | no |
| Allosteric Prediction | no (-1.092686502) |
| Ortholog in Animals | Mouse_ Kir3dl1 ( ortholog_many2many ) Mouse_ Kir3dl2 ( ortholog_many2many ) Rat_ Kir3dl1 ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | KIR3DL1, KIR3DL3, KIR2DL3, KIR2DS4, KIR2DL1, KIR2DL4, FCAR, LILRB2, LILRB5, LILRA2, LILRA4, LILRA6, LILRA5, NCR1, LILRB4, LILRB1, LILRA1, LILRB3, GP6, IGSF1, OSCAR, TARM1, VSTM1, LAIR2, A1BG |
| Tissue | NA |
| Tissue Specificity | Expressed in astrocytes. {ECO:0000269|PubMed:26928464}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3188286 rs633870 rs1048271 rs1377032475 rs3745902 rs3745903 |
| Subcellular location [CC] | Cell membrane; Single-pass type I membrane protein. |
| Mouse PG classification | NA |
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