Gene Information
Gene NameKIR2DS2
OrganismHomo sapiens (Human)
Gene Length304
Protein NamesKiller cell immunoglobulin-like receptor 2DS2 (CD158 antigen-like family member J) (NK receptor 183 ActI) (Natural killer-associated transcript 5) (NKAT-5) (p58 natural killer cell receptor clone CL-49) (p58 NK receptor CL-49) (CD antigen CD158j)
Target Namemhc class i nk cell receptor 2ds2
Target TypeClinical trial target
Gene Age3 ( ENSG00000274438 )
3 ( ENSG00000274518 )
3 ( ENSG00000275253 )
3 ( ENSG00000275452 )
3 ( ENSG00000275735 )
3 ( ENSG00000275737 )
3 ( ENSG00000276139 )
3 ( ENSG00000276258 )
3 ( ENSG00000276425 )
3 ( ENSG00000277885 )
3 ( ENSG00000278152 )
3 ( ENSG00000278300 )
Evolutionary StageNA
AlphaFoldDBP43631
Gene CardKIR2DS2
Uniprot IDP43631
PfamPF00047
In ASDno
Allosteric Predictionno (-0.991832941)
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1M4K  (X-ray  2.30A  4N8V  (X-ray  2.50A  7DUU  (X-ray  2.51A 
DBSNP rs189739973  rs1049626616  rs2262065  rs1063326 
Subcellular location [CC]Cell membrane;
Single-pass type I membrane protein.
Mouse PG classificationNA
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