| Gene Information | |
|---|---|
| Gene Name | KIND3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 667 |
| Protein Names | Fermitin family homolog 3 (Kindlin-3) (MIG2-like protein) (Unc-112-related protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q86UX7 |
| Gene Card | FERMT3 |
| Uniprot ID | Q86UX7 |
| Pfam | PF00373; PF18124; PF00169 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in lymph node. Expressed in thymus, spleen and leukocytes. Weakly expressed in placenta, small intestine, stomach, testis and lung. Overexpressed in B-cell malignancies. {ECO:0000269|PubMed:12697302, ECO:0000269|PubMed:12886250}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2YS3 (NMR - ) 6V97 (X-ray 2.38A ) 6V9G (X-ray 2.35A ) 7C3M (X-ray 3.60A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cell projection, podosome {ECO:0000250}. Note=Present in the F-actin surrounding ring structure of podosomes, which are specialized adhesion structures of hematopoietic cells. {ECO:0000250}. |
| Mouse PG classification | NA |
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