| Gene Information | |
|---|---|
| Gene Name | KIFC3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 833 |
| Protein Names | Kinesin-like protein KIFC3 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000140859 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9BVG8 |
| Gene Card | KIFC3 |
| Uniprot ID | Q9BVG8 |
| Pfam | PF00225 |
| In ASD | no |
| Allosteric Prediction | no (-0.947244873) |
| Ortholog in Animals | Alpaca_ KIFC3 ( ortholog_one2one ) Dog_ KIFC3 ( ortholog_one2one ) GuineaPig_ KIFC3 ( ortholog_one2one ) Macaque_ KIFC3 ( ortholog_one2one ) Mouse_ Kifc3 ( ortholog_one2one ) Pig_ KIFC3 ( ortholog_one2one ) Rat_ Kifc3 ( ortholog_one2one ) Rabbit_ KIFC3 ( ortholog_one2one ) |
| Ohnologs | KIFC2 |
| Paralogs | KIF27, KIF1C, KIF26B, KIF2B, KIF13A, KIF16B, KIF4A, KIF2A, KIF20A, KIF22, KIF3A, KIF13B, KIF5B, KIF1A, KIF3B, KIF3C, KIF1B, CENPE, KIF26A, KIF23, KIF7, KIF5A, KIF18B, KIF25, KIF9, KIF6, KIF14, KIF21B, KIF11, KIF15, KIFC1, KIF12, KIF4B, KIF24, KIF2C, KIF21A, KIF19, KIF17, KIF5C, KIF18A, KIFC2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 5WDE (X-ray 1.85A ) |
| DBSNP | rs17854089 |
| Subcellular location [CC] | Cell junction, adherens junction {ECO:0000269|PubMed:19041755}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:19041755}. Cytoplasmic vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Apical cell membrane. On membrane organelles immediately beneath the apical plasma membrane of renal tubular epithelial cells. Localized in the distal tubules and loops of Henle in the kidney, but not in the proximal tubules or the glomeruli, with stronger staining in the apical area of these epithelial cells (By similarity). Localizes along zonula adherens only at mature cell-cell contacts. {ECO:0000250}. |
| Mouse PG classification | NA |
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