| Gene Information | |
|---|---|
| Gene Name | EXD1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 514 |
| Protein Names | piRNA biogenesis protein EXD1 (Exonuclease 3'-5' domain-containing protein 1) (Exonuclease 3'-5' domain-like-containing protein 1) (Inactive exonuclease EXD1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000178997 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8NHP7 |
| Gene Card | EXD1 |
| Uniprot ID | Q8NHP7 |
| Pfam | PF01612 |
| In ASD | no |
| Allosteric Prediction | no (-1.314099161) |
| Ortholog in Animals | Alpaca_ EXD1 ( ortholog_one2one ) Dog_ EXD1 ( ortholog_one2one ) GuineaPig_ EXD1 ( ortholog_one2one ) Macaque_ EXD1 ( ortholog_one2one ) Mouse_ Exd1 ( ortholog_one2one ) Pig_ EXD1 ( ortholog_one2one ) Rat_ Exd1 ( ortholog_one2one ) Rabbit_ EXD1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | EXOSC10 |
| Tissue | testis |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.044444(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs522063 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250|UniProtKB:H9IUR0}. Note=Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. {ECO:0000250|UniProtKB:H9IUR0}. |
| Mouse PG classification | NA |
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