| Gene Information | |
|---|---|
| Gene Name | KIF7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1343 |
| Protein Names | Kinesin-like protein KIF7 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000166813 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q2M1P5 |
| Gene Card | KIF7 |
| Uniprot ID | Q2M1P5 |
| Pfam | PF00225 |
| In ASD | no |
| Allosteric Prediction | no (-0.920371608) |
| Ortholog in Animals | Alpaca_ KIF7 ( ortholog_one2one ) Dog_ KIF7 ( ortholog_one2one ) GuineaPig_ KIF7 ( ortholog_one2one ) Macaque_ KIF7 ( ortholog_one2one ) Mouse_ Kif7 ( ortholog_one2one ) Pig_ KIF7 ( ortholog_one2one ) Rat_ Kif7 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | KIF27, KIF1C, KIF26B, KIF2B, KIF13A, KIFC3, KIFC2, KIF16B, KIF4A, KIF2A, KIF20A, KIF22, KIF3A, KIF13B, KIF5B, KIF1A, KIF3B, KIF3C, KIF1B, CENPE, KIF26A, KIF23, KIF5A, KIF18B, KIF25, KIF9, KIF6, KIF14, KIF21B, KIF11, KIF15, KIFC1, KIF12, KIF4B, KIF24, KIF2C, KIF21A, KIF19, KIF17, KIF5C, KIF18A |
| Tissue | NA |
| Tissue Specificity | Embryonic stem cells, melanotic melanoma and Jurkat T-cells. Expressed in heart, lung, liver, kidney, testis, retina, placenta, pancreas, colon, small intestin, prostate and thymus. {ECO:0000269|PubMed:21633164}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2XT3 (X-ray 1.88A ) 4A14 (X-ray 1.60A ) 6MLQ (EM 4.20A ) 6MLR (EM 4.20A ) 7RX0 (EM 3.89A ) |
| DBSNP | rs8179065 rs180758272 rs115857753 rs137905815 rs149078926 rs143915145 rs138354681 rs3803530 rs146626238 rs138410949 rs12900805 rs886039282 rs147191956 rs142032413 rs202195179 |
| Subcellular location [CC] | Cell projection, cilium {ECO:0000269|PubMed:19592253}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:B7ZNG0}. Note=Localizes to the cilium tip. |
| Mouse PG classification | HPG |
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