Gene Information
Gene NameKIF22
OrganismHomo sapiens (Human)
Gene Length665
Protein NamesKinesin-like protein KIF22 (Kinesin-like DNA-binding protein) (Kinesin-like protein 4)
Target NameNA
Target TypeNA
Gene Age454 ( ENSG00000079616 )
Evolutionary StageEukaryota
AlphaFoldDBQ14807
Gene CardKIF22
Uniprot IDQ14807
PfamPF00225
In ASDno
Allosteric Predictionno (-0.309621839)
Ortholog in AnimalsAlpaca_ KIF22 ( ortholog_one2one )
Dog_ KIF22 ( ortholog_one2one )
GuineaPig_ KIF22 ( ortholog_one2one )
Macaque_ KIF22 ( ortholog_one2one )
Mouse_ Kif22 ( ortholog_one2one )
Pig_ KIF22 ( ortholog_one2one )
Rat_ Kif22 ( ortholog_one2one )
OhnologsNA
ParalogsKIF27, KIF1C, KIF26B, KIF2B, KIF13A, KIFC3, KIFC2, KIF16B, KIF4A, KIF2A, KIF20A, KIF3A, KIF13B, KIF5B, KIF1A, KIF3B, KIF3C, KIF1B, CENPE, KIF26A, KIF23, KIF7, KIF5A, KIF18B, KIF25, KIF9, KIF6, KIF14, KIF21B, KIF11, KIF15, KIFC1, KIF12, KIF4B, KIF24, KIF2C, KIF21A, KIF19, KIF17, KIF5C, KIF18A
TissueNA
Tissue SpecificityExpressed in bone, cartilage, joint capsule, ligament, skin, and primary cultured chondrocytes. {ECO:0000269|PubMed:22152677}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2EDU  (NMR  6NJE  (X-ray  2.20A 
DBSNP rs193922921  rs193922920  rs193922922  rs193922922  rs201659270 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:8599929}. Cytoplasm, cytoskeleton {ECO:0000305}.
Mouse PG classificationLPG
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