| Gene Information | |
|---|---|
| Gene Name | KIF21A |
| Organism | Homo sapiens (Human) |
| Gene Length | 1674 |
| Protein Names | Kinesin-like protein KIF21A (Kinesin-like protein KIF2) (Renal carcinoma antigen NY-REN-62) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000139116 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q7Z4S6 |
| Gene Card | KIF21A |
| Uniprot ID | Q7Z4S6 |
| Pfam | PF00225; PF00400 |
| In ASD | no |
| Allosteric Prediction | no (-0.688029025) |
| Ortholog in Animals | Alpaca_ KIF21A ( ortholog_one2one ) Dog_ KIF21A ( ortholog_one2one ) GuineaPig_ KIF21A ( ortholog_one2one ) Macaque_ KIF21A ( ortholog_one2one ) Mouse_ Kif21a ( ortholog_one2one ) Pig_ KIF21A ( ortholog_one2one ) Rat_ Kif21a ( ortholog_one2one ) Rabbit_ KIF21A ( ortholog_one2one ) |
| Ohnologs | KIF21B |
| Paralogs | KIF27, KIF1C, KIF26B, KIF2B, KIF13A, KIFC3, KIFC2, KIF16B, KIF4A, KIF2A, KIF20A, KIF22, KIF3A, KIF13B, KIF5B, KIF1A, KIF3B, KIF3C, KIF1B, CENPE, KIF26A, KIF23, KIF7, KIF5A, KIF18B, KIF25, KIF9, KIF6, KIF14, KIF21B, KIF11, KIF15, KIFC1, KIF12, KIF4B, KIF24, KIF2C, KIF19, KIF17, KIF5C, KIF18A |
| Tissue | substantia.nigra |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001990(Rat);0.05(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5D3A (X-ray 2.50A ) 5NFD (X-ray 2.18A ) 5YBU (X-ray 1.89A ) 5YBV (X-ray 2.12A ) 7KLJ (X-ray 1.52A ) |
| DBSNP | rs121912588 rs121912590 rs121912589 rs121912586 rs121912585 rs121912587 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q9QXL2}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q9QXL2}. Cell projection, axon {ECO:0000250|UniProtKB:Q9QXL2}. Note=In neurons, localized to axons and dendrites. {ECO:0000250|UniProtKB:Q9QXL2}. |
| Mouse PG classification | NA |
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