| Gene Information | |
|---|---|
| Gene Name | CELA1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 258 |
| Protein Names | Chymotrypsin-like elastase family member 1 (EC 3.4.21.36) (Elastase-1) (Pancreatic elastase 1) |
| Target Name | chymotrypsin-like elastase family member 1 |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000139610 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9UNI1 |
| Gene Card | CELA1 |
| Uniprot ID | Q9UNI1 |
| Pfam | PF00089 |
| In ASD | yes |
| Allosteric Prediction | yes (0.135170076) |
| Ortholog in Animals | Alpaca_ CELA1 ( ortholog_one2one ) Dog_ CELA1 ( ortholog_one2one ) GuineaPig_ CELA1 ( ortholog_one2one ) Macaque_ CELA1 ( ortholog_one2one ) Mouse_ Cela1 ( ortholog_one2one ) Pig_ CELA1 ( ortholog_one2one ) Rabbit_ CELA1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PRTN3, ELANE, CELA3A, CELA3B, CELA2A, CELA2B |
| Tissue | NA |
| Tissue Specificity | Basal layers of epidermis (at protein level). Not expressed in the pancreas. {ECO:0000269|PubMed:10620133}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs17860287 rs17860299 rs17860300 rs17860364 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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