| Gene Information | |
|---|---|
| Gene Name | KIAA1987 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1834 |
| Protein Names | Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q8IY92 |
| Gene Card | SLX4 |
| Uniprot ID | Q8IY92 |
| Pfam | PF00651; PF09494 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002990(Rat);0.018182(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4M7C (X-ray 2.05A ) 4UYI (X-ray 1.86A ) 4ZOU (X-ray 2.15A ) 7BU5 (X-ray 1.80A ) |
| DBSNP | rs141167501 rs137976282 rs147826749 rs79842542 rs138615800 rs115694169 rs113490934 rs551823420 rs74319927 rs149126845 rs765859186 rs371825444 rs772504776 rs77985244 rs140600202 rs149584080 rs145137472 rs117707719 rs114014006 rs863224277 rs114472821 rs138798067 rs144273492 rs714181 rs144647122 rs3827530 rs3810813 rs149011965 rs1596520811 rs140051968 rs17136464 rs141567438 rs372321470 rs77021998 rs7196345 rs761226343 rs767720336 rs111738042 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:19596235, ECO:0000269|PubMed:19596236}. Note=Localizes to sites of DNA damage. |
| Mouse PG classification | NA |
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