| Gene Information | |
|---|---|
| Gene Name | PPP2R3A |
| Organism | Homo sapiens (Human) |
| Gene Length | 1150 |
| Protein Names | Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha (PP2A subunit B isoform PR72/PR130) (PP2A subunit B isoform R3 isoform) (PP2A subunit B isoforms B''-PR72/PR130) (PP2A subunit B isoforms B72/B130) (Serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000073711 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q06190 |
| Gene Card | PPP2R3A |
| Uniprot ID | Q06190 |
| Pfam | PF17958; PF13499 |
| In ASD | no |
| Allosteric Prediction | yes (0.233797552) |
| Ortholog in Animals | Alpaca_ PPP2R3A ( ortholog_one2one ) Dog_ PPP2R3A ( ortholog_one2one ) GuineaPig_ PPP2R3A ( ortholog_one2one ) Macaque_ PPP2R3A ( ortholog_one2one ) Mouse_ Ppp2r3a ( ortholog_one2one ) Pig_ PPP2R3A ( ortholog_one2one ) Rat_ Ppp2r3a ( ortholog_one2one ) Rabbit_ PPP2R3A ( ortholog_one2one ) |
| Ohnologs | PPP2R3B |
| Paralogs | PPP2R3B |
| Tissue | artery, heart, left.atrium, left.ventricle, mitral.valve, penis, pulmonary.valve, tongue |
| Tissue Specificity | Expressed in heart, brain, placenta, lung, muscle and kidney. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002657(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4I5J (X-ray 2.09A ) 4I5K (X-ray 2.90A ) |
| DBSNP | rs9814557 rs57374999 rs36020282 rs6779903 rs34901937 rs17197552 rs9826032 rs16843645 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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