| Gene Information | |
|---|---|
| Gene Name | WNT10B |
| Organism | Homo sapiens (Human) |
| Gene Length | 389 |
| Protein Names | Protein Wnt-10b (Protein Wnt-12) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000169884 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O00744 |
| Gene Card | WNT10B |
| Uniprot ID | O00744 |
| Pfam | PF00110 |
| In ASD | no |
| Allosteric Prediction | no (-0.502967879) |
| Ortholog in Animals | Alpaca_ WNT10B ( ortholog_one2one ) Dog_ WNT10B ( ortholog_one2one ) GuineaPig_ WNT10B ( ortholog_one2one ) Macaque_ WNT10B ( ortholog_one2one ) Mouse_ Wnt10b ( ortholog_one2one ) Pig_ WNT10B ( ortholog_one2one ) Rat_ Wnt10b ( ortholog_one2one ) Rabbit_ WNT10B ( ortholog_one2one ) |
| Ohnologs | WNT10A |
| Paralogs | WNT5A, WNT6, WNT3, WNT4, WNT2B, WNT2, WNT9B, WNT16, WNT8B, WNT11, WNT3A, WNT7B, WNT5B, WNT10A, WNT9A, WNT7A, WNT1, WNT8A |
| Tissue | amygdala, caudate.nucleus, cerebral.cortex, nucleus.accumbens, putamen |
| Tissue Specificity | Detected in most adult tissues. Highest levels were found in heart and skeletal muscle. Low levels are found in brain. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs151284263 rs779326570 rs146010731 rs35034312 rs121918349 |
| Subcellular location [CC] | Secreted, extracellular space, extracellular matrix {ECO:0000305}. Secreted {ECO:0000269|PubMed:26902720}. |
| Mouse PG classification | LPG |
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