| Gene Information | |
|---|---|
| Gene Name | RAP2C |
| Organism | Homo sapiens (Human) |
| Gene Length | 183 |
| Protein Names | Ras-related protein Rap-2c (EC 3.6.5.2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000123728 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9Y3L5 |
| Gene Card | RAP2C |
| Uniprot ID | Q9Y3L5 |
| Pfam | PF00071 |
| In ASD | no |
| Allosteric Prediction | no (-0.367069732) |
| Ortholog in Animals | Alpaca_ RAP2C ( ortholog_one2one ) Dog_ RAP2C ( ortholog_one2one ) GuineaPig_ RAP2C ( ortholog_one2one ) Macaque_ RAP2C ( ortholog_one2one ) Mouse_ Rap2c ( ortholog_one2one ) Pig_ RAP2C ( ortholog_one2one ) Rat_ Rap2c ( ortholog_one2one ) Rabbit_ RAP2C ( ortholog_one2one ) |
| Ohnologs | RAP2A, RAP2B |
| Paralogs | RRAS, RHEB, KRAS, DIRAS1, RRAS2, RAP2B, HRAS, RERG, RASL12, RRAD, RIT1, DIRAS2, ERAS, NKIRAS1, RALB, RASD2, GEM, DIRAS3, MRAS, RAP2A, RASD1, REM1, NKIRAS2, RALA, RAP1A, RASL11B, RAP1B, RASL10A, RASL11A, REM2, RERGL, RIT2, RHEBL1, NRAS, RASL10B |
| Tissue | NA |
| Tissue Specificity | Expressed in liver, skeletal muscle, prostate, uterus, rectum, stomach, and bladder and to a lower extent in brain, kidney, pancreas, and bone marrow. Expressed in mononuclear leukocytes and megakaryocytes. {ECO:0000269|PubMed:16213650, ECO:0000269|PubMed:17447155}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:17447155}. Recycling endosome membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}. |
| Mouse PG classification | NA |
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