Gene Information
Gene NameONECUT1
OrganismHomo sapiens (Human)
Gene Length465
Protein NamesHepatocyte nuclear factor 6 (HNF-6) (One cut domain family member 1) (One cut homeobox 1)
Target NameNA
Target TypeNA
Gene Age645 ( ENSG00000169856 )
Evolutionary StageEumetazoa
AlphaFoldDBQ9UBC0
Gene CardONECUT1
Uniprot IDQ9UBC0
PfamPF02376; PF00046
In ASDno
Allosteric Predictionno (-0.885673852)
Ortholog in AnimalsAlpaca_ ONECUT1 ( ortholog_one2one )
Dog_ ONECUT1 ( ortholog_one2one )
GuineaPig_ ONECUT1 ( ortholog_one2one )
Macaque_ ONECUT1 ( ortholog_one2one )
Mouse_ Onecut1 ( ortholog_one2one )
Pig_ ONECUT1 ( ortholog_one2one )
Rat_ Onecut1 ( ortholog_one2one )
Rabbit_ ONECUT1 ( ortholog_one2one )
OhnologsONECUT2, ONECUT3
ParalogsONECUT3, ONECUT2
Tissuegall.bladder, liver, pancreas
Tissue SpecificityHighly expressed in liver;
lower expression in testis and skin.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.1(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs74805019 
Subcellular location [CC]Nucleus.
Mouse PG classificationNA
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