| Gene Information | |
|---|---|
| Gene Name | KIAA1650 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1731 |
| Protein Names | SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9BYB0 |
| Gene Card | SHANK3 |
| Uniprot ID | Q9BYB0 |
| Pfam | PF12796; PF17820; PF00536; PF07653 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in the cerebral cortex and the cerebellum. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6CPK (NMR - ) 7C7I (X-ray 2.28A ) 7C7J (X-ray 2.39A ) |
| DBSNP | rs1336089966 rs397514705 rs1232069989 rs766856815 rs9616915 rs376862893 rs1314696433 rs387906933 rs1340094921 rs530255181 rs767058690 rs769454362 rs139686326 rs750186589 rs757572910 rs201483867 rs200087210 rs201973139 rs773395828 rs1389307970 rs1224063430 rs1481014682 rs749130556 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:24132240}. Postsynaptic density {ECO:0000269|PubMed:24132240}. Cell projection, dendritic spine {ECO:0000250}. Note=In neuronal cells, extends into the region subjacent to the postsynaptic density (PSD). {ECO:0000250}. |
| Mouse PG classification | NA |
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