| Gene Information | |
|---|---|
| Gene Name | KIAA1590 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1317 |
| Protein Names | Kinesin-like protein KIF16B (Sorting nexin-23) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q96L93 |
| Gene Card | KIF16B |
| Uniprot ID | Q96L93 |
| Pfam | PF00498; PF00225; PF00787 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Primarily expressed in brain. Also present in kidney, liver, intestine, placenta, leukocytes, heart and skeletal muscle (at protein level). {ECO:0000269|PubMed:15882625}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2V14 (X-ray 2.20A ) 6EE0 (X-ray 2.52A ) |
| DBSNP | rs2236145 rs2236144 rs8116503 rs6034464 rs8123195 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton {ECO:0000305}. Early endosome membrane {ECO:0000269|PubMed:15882625}. Cytoplasm {ECO:0000269|PubMed:18445686}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:18445686}. Note=It is unclear whether association with endosomes is mediated via phosphatidylinositol 3-phosphate (PtdIns(3)P)-binding or via its interaction with RAB14. {ECO:0000269|PubMed:15882625}. |
| Mouse PG classification | NA |
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