| Gene Information | |
|---|---|
| Gene Name | KIAA1533 |
| Organism | Homo sapiens (Human) |
| Gene Length | 724 |
| Protein Names | Protein Aster-A (GRAM domain-containing protein 1A) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q96CP6 |
| Gene Card | GRAMD1A |
| Uniprot ID | Q96CP6 |
| Pfam | PF02893; PF16016 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in liver. {ECO:0000269|PubMed:27585821}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:29469807}; Single-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000269|PubMed:29469807}; Single-pass membrane protein {ECO:0000255}. Cytoplasmic vesicle, autophagosome {ECO:0000269|PubMed:31222192}. Note=In lipid-poor conditions localizes to the ER membrane and is recruited to endoplasmic reticulum-plasma membrane contact sites (EPCS) in response to excess cholesterol in the PM (By similarity). Localizes to distinct EPCS than GRAMD2A and ESYT2/3 (PubMed:29469807). {ECO:0000250|UniProtKB:Q8VEF1, ECO:0000269|PubMed:29469807}. |
| Mouse PG classification | NA |
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