Gene Information
Gene NameSLC22A13
OrganismHomo sapiens (Human)
Gene Length551
Protein NamesSolute carrier family 22 member 13 (Organic anion transporter 10) (OAT10) (Organic cation transporter-like 3) (ORCTL-3) (ORCTL3)
Target NameNA
Target TypeNA
Gene Age1488 ( ENSG00000172940 )
Evolutionary StageEuk+Bac
AlphaFoldDBQ9Y226
Gene CardSLC22A13
Uniprot IDQ9Y226
PfamPF00083
In ASDno
Allosteric Predictionno (-0.550123174)
Ortholog in AnimalsAlpaca_ SLC22A13 ( ortholog_one2one )
Dog_ SLC22A13 ( ortholog_one2one )
Macaque_ SLC22A13 ( ortholog_one2one )
Mouse_ Slc22a13 ( ortholog_one2many )
Mouse_ Slc22a13b ( ortholog_one2many )
Pig_ SLC22A13 ( ortholog_one2one )
Rat_ Slc22a13 ( ortholog_one2many )
OhnologsSLC22A2, SLC22A3, SLC22A1, SLC22A6
ParalogsSLC22A24, SLC22A12, SLC22A1, SLC22A6, SVOP, SLC22A17, SLC22A7, SLC22A11, SLC22A23, SLC22A2, SLC22A25, SLC22A15, SLC22A9, SLC22A4, SLC22A5, SLC22A3, SLC22A16, SLC22A8, SVOPL, SLC22A31, SLC22A14, SLC22A10
Tissuekidney
Tissue SpecificityUbiquitous (PubMed:10072596). Highly expressed in kidneys and to a weaker extent in brain, heart, and intestine (PubMed:18411268). In kidneys, expressed in proximal convoluted tubule (PubMed:18411268, PubMed:31780526, PubMed:35462902). In kidneys, also expressed in cortical collecting duct, whereas glomerulus and thick ascending limb exhibit no expression (PubMed:18411268). {ECO:0000269|PubMed:10072596, ECO:0000269|PubMed:18411268, ECO:0000269|PubMed:31780526, ECO:0000269|PubMed:35462902}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs17853496  rs17857080 
Subcellular location [CC]Apical cell membrane {ECO:0000269|PubMed:18411268, ECO:0000269|PubMed:31780526, ECO:0000269|PubMed:35144162, ECO:0000269|PubMed:35462902};
Multi-pass membrane protein {ECO:0000305}.
Mouse PG classificationNA
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