| Gene Information | |
|---|---|
| Gene Name | UNQ650/PRO1280 |
| Organism | Homo sapiens (Human) |
| Gene Length | 484 |
| Protein Names | Suppressor of fused homolog (SUFUH) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9UMX1 |
| Gene Card | SUFU |
| Uniprot ID | Q9UMX1 |
| Pfam | PF05076; PF12470 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous in adult tissues. Detected in osteoblasts of the perichondrium in the developing limb of 12-week old embryos. Isoform 1 is detected in fetal brain, lung, kidney and testis. Isoform 2 is detected in fetal testis, and at much lower levels in fetal brain, lung and kidney. {ECO:0000269|PubMed:10559945, ECO:0000269|PubMed:10564661}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.046154(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1M1L (X-ray 2.65A ) 4BL8 (X-ray 3.04A ) 4BL9 (X-ray 2.80A ) 4BLA (X-ray 3.50A ) 4BLB (X-ray 2.80A ) 4BLD (X-ray 2.80A ) 4KM8 (X-ray 2.26A ) 4KM9 (X-ray 3.19A ) 4KMD (X-ray 1.70A ) 4KMH (X-ray 3.04A ) |
| DBSNP | rs28942088 rs745793517 rs1554852272 rs149016373 rs574002050 rs34135067 rs1401882800 rs1554854758 rs772598739 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:10559945, ECO:0000269|PubMed:28965847}. Nucleus {ECO:0000269|PubMed:10559945, ECO:0000269|PubMed:28965847}. |
| Mouse PG classification | NA |
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