| Gene Information | |
|---|---|
| Gene Name | MKPX |
| Organism | Homo sapiens (Human) |
| Gene Length | 184 |
| Protein Names | Dual specificity protein phosphatase 22 (EC 3.1.3.16) (EC 3.1.3.48) (JNK-stimulatory phosphatase-1) (JSP-1) (Low molecular weight dual specificity phosphatase 2) (LMW-DSP2) (Mitogen-activated protein kinase phosphatase x) (MAP kinase phosphatase x) (MKP-x) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9NRW4 |
| Gene Card | DUSP22 |
| Uniprot ID | Q9NRW4 |
| Pfam | PF00782 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Highest expression seen in heart, placenta, lung, liver, kidney and pancreas. {ECO:0000269|PubMed:11717427}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1WRM (X-ray 1.50A ) 4WOH (X-ray 1.34A ) 6L1S (X-ray 1.36A ) 6LMY (X-ray 1.50A ) 6LOT (X-ray 1.69A ) 6LOU (X-ray 1.53A ) 6LVQ (X-ray 1.38A ) 7C8S (X-ray 1.31A ) |
| DBSNP | rs7768224 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:20553486}. |
| Mouse PG classification | NA |
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