| Gene Information | |
|---|---|
| Gene Name | KIAA0551 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1360 |
| Protein Names | TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9UKE5 |
| Gene Card | TNIK |
| Uniprot ID | Q9UKE5 |
| Pfam | PF00780; PF00069 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed ubiquitously. Highest levels observed in heart, brain and skeletal muscle. Expressed in normal colonic epithelia and colorectal cancer tissues. {ECO:0000269|PubMed:10521462, ECO:0000269|PubMed:19816403}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2X7F (X-ray 2.80A ) 5AX9 (X-ray 2.40A ) 5CWZ (X-ray 2.90A ) 5D7A (X-ray 2.90A ) 6RA5 (X-ray 2.90A ) 6RA7 (X-ray 1.20A ) |
| DBSNP | rs55778284 rs35090763 rs17857452 |
| Subcellular location [CC] | Nucleus. Cytoplasm. Recycling endosome. Cytoplasm, cytoskeleton. Note=Associated with recycling endosomes and the cytoskeletal fraction upon RAP2A overexpression. |
| Mouse PG classification | NA |
| click here to return to the previous page | |