| Gene Information | |
|---|---|
| Gene Name | KIAA1319 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1203 |
| Protein Names | Cingulin |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9P2M7 |
| Gene Card | CGN |
| Uniprot ID | Q9P2M7 |
| Pfam | PF01576 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Localized on the cytoplasmic face of tight junctions of polarized epithelia and some endothelia. Expressed in pancreas, kidney, liver and lung, but not in skeletal muscle, placenta, brain or heart. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12038198 |
| Subcellular location [CC] | Cell junction, tight junction {ECO:0000250|UniProtKB:P59242}. Note=Localizes to the apical junction complex composed of tight and adherens junctions (By similarity). Colocalizes with SPEF1 at sites of cell-cell contact in intestinal epithelial cells (PubMed:12023291). {ECO:0000250|UniProtKB:P59242, ECO:0000269|PubMed:12023291}. |
| Mouse PG classification | NA |
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