| Gene Information | |
|---|---|
| Gene Name | PPP1R3A |
| Organism | Homo sapiens (Human) |
| Gene Length | 1122 |
| Protein Names | Protein phosphatase 1 regulatory subunit 3A (Protein phosphatase 1 glycogen-associated regulatory subunit) (Protein phosphatase type-1 glycogen targeting subunit) (RG1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000154415 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q16821 |
| Gene Card | PPP1R3A |
| Uniprot ID | Q16821 |
| Pfam | PF03370 |
| In ASD | no |
| Allosteric Prediction | yes (0.460609155) |
| Ortholog in Animals | Alpaca_ PPP1R3A ( ortholog_one2one ) Dog_ PPP1R3A ( ortholog_one2one ) GuineaPig_ PPP1R3A ( ortholog_one2one ) Macaque_ PPP1R3A ( ortholog_one2one ) Mouse_ Ppp1r3a ( ortholog_one2one ) Pig_ PPP1R3A ( ortholog_one2one ) Rat_ Ppp1r3a ( ortholog_one2one ) Rabbit_ PPP1R3A ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PPP1R3G, PPP1R3D, PPP1R3C, PPP1R3B, PPP1R3E, PPP1R3F |
| Tissue | heart, skeletal.muscle, atrium, left.ventricle |
| Tissue Specificity | Skeletal muscle and heart. {ECO:0000269|PubMed:9726244}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5ZQV (X-ray 2.95A ) |
| DBSNP | rs8192687 rs7801819 rs2974942 rs2974944 rs35067467 rs4304271 rs2974938 rs1800000 rs1799999 rs35449651 |
| Subcellular location [CC] | Membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. |
| Mouse PG classification | HPG |
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