| Gene Information | |
|---|---|
| Gene Name | PKD2L2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 624 |
| Protein Names | Polycystic kidney disease 2-like 2 protein (Polycystin-2L2) (Polycystin-L2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000078795 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9NZM6 |
| Gene Card | PKD2L2 |
| Uniprot ID | Q9NZM6 |
| Pfam | PF08016; PF20519 |
| In ASD | no |
| Allosteric Prediction | no (-0.685661105) |
| Ortholog in Animals | Alpaca_ PKD2L2 ( ortholog_one2one ) Dog_ PKD2L2 ( ortholog_one2one ) GuineaPig_ PKD2L2 ( ortholog_one2one ) Macaque_ PKD2L2 ( ortholog_one2one ) Mouse_ Pkd2l2 ( ortholog_one2one ) Pig_ PKD2L2 ( ortholog_one2one ) Rat_ Pkd2l2 ( ortholog_one2one ) Rabbit_ PKD2L2 ( ortholog_one2one ) |
| Ohnologs | PKD2L1, PKD2 |
| Paralogs | PKDREJ, PKD1L2, DENND5B, DENND5A, PKD2L1, LOXHD1, PKD1L3, PKD1L1, PKD1, PKD2 |
| Tissue | testis |
| Tissue Specificity | According to PubMed:10602361, expressed only in testis. According to PubMed:10756092, expressed also in brain and kidney. Isoform 2 is found only in transformed lymphoblasts. Isoform 3 is found in all tissues tested. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs1880458 rs12187140 |
| Subcellular location [CC] | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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