| Gene Information | |
|---|---|
| Gene Name | CBLC |
| Organism | Homo sapiens (Human) |
| Gene Length | 474 |
| Protein Names | E3 ubiquitin-protein ligase CBL-C (EC 2.3.2.27) (RING finger protein 57) (RING-type E3 ubiquitin transferase CBL-C) (SH3-binding protein CBL-3) (SH3-binding protein CBL-C) (Signal transduction protein CBL-C) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000142273 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q9ULV8 |
| Gene Card | CBLC |
| Uniprot ID | Q9ULV8 |
| Pfam | PF02262; PF02761; PF02762 |
| In ASD | no |
| Allosteric Prediction | no (-0.053430173) |
| Ortholog in Animals | Alpaca_ CBLC ( ortholog_one2one ) Dog_ CBLC ( ortholog_one2one ) GuineaPig_ CBLC ( ortholog_one2one ) Macaque_ CBLC ( ortholog_one2one ) Mouse_ Cblc ( ortholog_one2one ) Pig_ CBLC ( ortholog_one2one ) Rat_ Cblc ( ortholog_one2one ) |
| Ohnologs | CBL, CBLB |
| Paralogs | CBL, CBLB |
| Tissue | pancreas, small.intestine |
| Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:10362357}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3OP0 (X-ray 2.52A ) 3VRN (X-ray 1.64A ) 3VRO (X-ray 1.80A ) 3VRP (X-ray 1.52A ) 3VRQ (X-ray 2.39A ) 3VRR (X-ray 2.00A ) |
| DBSNP | rs3208856 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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