| Gene Information | |
|---|---|
| Gene Name | ULBP6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 246 |
| Protein Names | UL16-binding protein 6 (Retinoic acid early transcript 1L protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q5VY80 |
| Gene Card | RAET1L |
| Uniprot ID | Q5VY80 |
| Pfam | PF00129 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed (PubMed:11827464). Expressed in trachea (PubMed:19658097). Constitutively expressed in peripheral blood mononuclear cells, including B-cells and natural killer cells, as well as CD4+ and CD8+ T-cells and monocytes. Tends to be up-regulated in various lymphoid malignancies, including chronic lymphocytic leukemia (PubMed:28559451). {ECO:0000269|PubMed:11827464, ECO:0000269|PubMed:19658097, ECO:0000269|PubMed:28559451}. |
| Pharmacological Animal Models | 0.175380(Chimpanzee);NULL(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4S0U (X-ray 2.35A ) |
| DBSNP | rs1543547 rs912565 rs1555696 rs61730071 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:19658097}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:19658097}. Endoplasmic reticulum {ECO:0000250|UniProtKB:Q9BZM6}. Note=In CMV-infected fibroblasts, detected intracellularly. {ECO:0000269|PubMed:19658097}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |