| Gene Information | |
|---|---|
| Gene Name | SGK223 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1406 |
| Protein Names | Inactive tyrosine-protein kinase PRAG1 (PEAK1-related kinase-activating pseudokinase 1) (Pragmin) (Sugen kinase 223) (SgK223) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q86YV5 |
| Gene Card | PRAG1 |
| Uniprot ID | Q86YV5 |
| Pfam | PF00069 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5VE6 (X-ray 2.95A ) |
| DBSNP | rs55764617 rs56290960 rs34346032 rs3896980 rs4840955 rs4840953 rs55994745 rs56351643 rs56207906 rs56215812 rs56289289 rs28533138 rs12549973 rs1314830862 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250|UniProtKB:D3ZMK9}. Cell junction, focal adhesion {ECO:0000269|PubMed:27116701}. Nucleus {ECO:0000250|UniProtKB:Q571I4}. Note=Colocalized with NOTCH1 in the nucleus. {ECO:0000250|UniProtKB:Q571I4}. |
| Mouse PG classification | NA |
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