| Gene Information | |
|---|---|
| Gene Name | MGLUR7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 915 |
| Protein Names | Metabotropic glutamate receptor 7 (mGluR7) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q14831 |
| Gene Card | GRM7 |
| Uniprot ID | Q14831 |
| Pfam | PF00003; PF01094; PF07562 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in many areas of the brain, especially in the cerebral cortex, hippocampus, and cerebellum. Expression of GRM7 isoforms in non-neuronal tissues appears to be restricted to isoform 3 and isoform 4. {ECO:0000269|PubMed:12052533, ECO:0000269|PubMed:8840028}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3MQ4 (X-ray 2.80A ) 5C5C (X-ray 1.86A ) 7EPC (EM 4.00A ) 7EPD (EM 3.90A ) |
| DBSNP | rs1114167298 rs2229902 rs7634846 rs769709112 rs1114167300 rs1114167301 rs1485174 rs746833089 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:33500274}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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