Gene Information
Gene NameKIAA1142
OrganismHomo sapiens (Human)
Gene Length591
Protein NamesSerine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBO96013
Gene CardPAK4
Uniprot IDO96013
PfamPF00786; PF00069
In ASDyes
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityHighest expression in prostate, testis and colon.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2BVA  (X-ray  2.30A  )  2CDZ  (X-ray  2.30A  )  2J0I  (X-ray  1.60A  )  2OV2  (X-ray  2.10A  )  2Q0N  (X-ray  1.75A  )  2X4Z  (X-ray  2.10A  )  4APP  (X-ray  2.20A  )  4FIE  (X-ray  3.11A  )  4FIF  (X-ray  2.60A  )  4FIG  (X-ray  3.01A  )  4FIH  (X-ray  1.97A  )  4FII  (X-ray  2.00A  )  4FIJ  (X-ray  2.30A  )  4JDH  (X-ray  2.00A  )  4JDI  (X-ray  1.85A  )  4JDJ  (X-ray  2.30A  )  4JDK  (X-ray  2.40A  )  4L67  (X-ray  2.80A  )  4NJD  (X-ray  2.50A  )  4O0V  (X-ray  2.80A  )  4O0X  (X-ray  2.48A  )  4O0Y  (X-ray  2.20A  )  4XBR  (X-ray  2.94A  )  4XBU  (X-ray  2.06A  )  5BMS  (X-ray  2.90A  )  5I0B  (X-ray  3.09A  )  5UPK  (X-ray  2.40A  )  5UPL  (X-ray  3.00A  )  5VED  (X-ray  2.30A  )  5VEE  (X-ray  2.50A  )  5VEF  (X-ray  1.75A  )  5XVA  (X-ray  1.85A  )  5XVF  (X-ray  2.65A  )  5XVG  (X-ray  2.10A  )  5ZJW  (X-ray  1.80A  )  6WLX  (X-ray  2.20A  )  6WLY  (X-ray  1.90A  )  7CMB  (X-ray  2.59A  )  7CP3  (X-ray  2.90A  )  7CP4  (X-ray  2.50A  ) 
DBSNP rs56099436  rs35655056 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:12356872}. Note=Seems to shuttle between cytoplasmic compartments depending on the activating effector. For example, can be found on the cell periphery after activation of growth-factor or integrin-mediated signaling pathways. {ECO:0000269|PubMed:12356872}.
Mouse PG classificationNA
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