| Gene Information | |
|---|---|
| Gene Name | DESI1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 168 |
| Protein Names | Desumoylating isopeptidase 1 (DeSI-1) (EC 3.4.-.-) (PPPDE peptidase domain-containing protein 2) (Polyubiquitinated substrate transporter) (POST) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000100418 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q6ICB0 |
| Gene Card | DESI1 |
| Uniprot ID | Q6ICB0 |
| Pfam | PF05903 |
| In ASD | no |
| Allosteric Prediction | no (-1.420709108) |
| Ortholog in Animals | Alpaca_ DESI1 ( ortholog_one2one ) GuineaPig_ DESI1 ( ortholog_one2one ) Macaque_ DESI1 ( ortholog_one2one ) Mouse_ Desi1 ( ortholog_one2one ) Pig_ DESI1 ( ortholog_one2one ) Rat_ Desi1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | DESI2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);0.020650(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3EBQ (X-ray 1.90A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:29666234}. Nucleus {ECO:0000269|PubMed:29666234}. Note=Shuttles between the nucleus and the cytoplasm; exported from the nucleus in a XPO1/CRM1-dependent manner via its nuclear export signal motifs. {ECO:0000269|PubMed:29666234}. |
| Mouse PG classification | NA |
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