| Gene Information | |
|---|---|
| Gene Name | MT-ND1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 318 |
| Protein Names | NADH-ubiquinone oxidoreductase chain 1 (EC 7.1.1.2) (NADH dehydrogenase subunit 1) |
| Target Name | nadh-ubiquinone oxidoreductase chain 1 |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000198888 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P03886 |
| Gene Card | MT-ND1 |
| Uniprot ID | P03886 |
| Pfam | PF00146 |
| In ASD | no |
| Allosteric Prediction | yes (0.053268146) |
| Ortholog in Animals | Alpaca_ ND1 ( ortholog_one2one ) Alpaca_ MT-ND1 ( ortholog_one2one ) GuineaPig_ ND1 ( ortholog_one2one ) Macaque_ ND1 ( ortholog_one2many ) Mouse_ mt-Nd1 ( ortholog_one2one ) Pig_ ND1 ( ortholog_one2one ) Rat_ Mt-nd1 ( ortholog_one2one ) Rabbit_ ND1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.375913(Chimpanzee);0.341715(Mouse);0.643233(Rat);0.267767(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5XTC (EM 3.70A ) 5XTD (EM 3.70A ) |
| DBSNP | rs2853516 rs1556422722 rs41460449 rs201212638 rs199476120 rs199476118 rs2854133 rs2854135 rs199476123 rs199476121 rs199476119 rs1599988 |
| Subcellular location [CC] | Mitochondrion inner membrane {ECO:0000250|UniProtKB:P03887}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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