Gene Information
Gene NameKIAA1097
OrganismHomo sapiens (Human)
Gene Length942
Protein NamesUbiquitin carboxyl-terminal hydrolase 33 (EC 3.4.19.12) (Deubiquitinating enzyme 33) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (VHL-interacting deubiquitinating enzyme 1) (hVDU1)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ8TEY7
Gene CardUSP33
Uniprot IDQ8TEY7
PfamPF06337; PF00443; PF02148
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityWidely expressed. {ECO:0000269|PubMed:11739384}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.002101(Rat);0.02(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2UZG  (NMR 
DBSNP NA 
Subcellular location [CC]Cytoplasm, perinuclear region {ECO:0000269|PubMed:19118533}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:23486064}. Note=Associates with centrosomes predominantly in S and G2 phases but less in G1 phase (PubMed:23486064). {ECO:0000269|PubMed:23486064}.;
[Isoform 3]: Golgi apparatus {ECO:0000269|PubMed:21801292}.
Mouse PG classificationNA
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