| Gene Information | |
|---|---|
| Gene Name | CUL4A |
| Organism | Homo sapiens (Human) |
| Gene Length | 759 |
| Protein Names | Cullin-4A (CUL-4A) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000139842 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q13619 |
| Gene Card | CUL4A |
| Uniprot ID | Q13619 |
| Pfam | PF00888; PF10557 |
| In ASD | yes |
| Allosteric Prediction | yes (0.681045283) |
| Ortholog in Animals | Alpaca_ CUL4A ( ortholog_one2many ) Dog_ CUL4A ( ortholog_one2one ) GuineaPig_ CUL4A ( ortholog_one2one ) Macaque_ CUL4A ( ortholog_one2one ) Mouse_ Cul4a ( ortholog_one2one ) Pig_ CUL4A ( ortholog_one2one ) Rat_ Cul4a ( ortholog_one2one ) Rabbit_ CUL4A ( ortholog_one2one ) |
| Ohnologs | CUL4B |
| Paralogs | CUL3, CACUL1, CUL2, ANAPC2, CUL1, CUL5, CUL4B |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.138865(Chimpanzee);0.148384(Mouse);0.016253(Rat);0.079039(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2HYE (X-ray 3.10A ) 4A0K (X-ray 5.93A ) 7OKQ (EM 8.40A ) 7OPC (EM 3.00A ) 7OPD (EM 3.00A ) |
| DBSNP | rs2302757 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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