| Gene Information | |
|---|---|
| Gene Name | B4GALT4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 344 |
| Protein Names | Beta-1,4-galactosyltransferase 4 (Beta-1,4-GalTase 4) (Beta4Gal-T4) (b4Gal-T4) (EC 2.4.1.-) (Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase) (Lactotriaosylceramide beta-1,4-galactosyltransferase) (EC 2.4.1.275) (N-acetyllactosamine synthase) (EC 2.4.1.90) (Nal synthase) (UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 4) (UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 4) |
| Target Name | beta-1,4-galactosyltransferase 4 |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000121578 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O60513 |
| Gene Card | B4GALT4 |
| Uniprot ID | O60513 |
| Pfam | PF02709; PF13733 |
| In ASD | no |
| Allosteric Prediction | no (-0.550869988) |
| Ortholog in Animals | Alpaca_ B4GALT4 ( ortholog_one2one ) Dog_ B4GALT4 ( ortholog_one2one ) GuineaPig_ B4GALT4 ( ortholog_one2one ) Macaque_ B4GALT4 ( ortholog_one2many ) Mouse_ B4galt4 ( ortholog_one2one ) Pig_ B4GALT4 ( ortholog_one2one ) Rat_ B4galt4 ( ortholog_one2one ) Rabbit_ B4GALT4 ( ortholog_one2one ) |
| Ohnologs | B4GALT2, B4GALT3 |
| Paralogs | B4GALT5, B4GALT3, B4GALT1, B4GALT6, B4GALT2, B4GALT7 |
| Tissue | NA |
| Tissue Specificity | Highest expression is observed in placenta, pancreas, kidney and heart (PubMed:9792633). Expressed in corneal epithelial cells (PubMed:17690104). {ECO:0000269|PubMed:17690104, ECO:0000269|PubMed:9792633}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs3764779 |
| Subcellular location [CC] | Golgi apparatus membrane {ECO:0000269|PubMed:32827291}; Single-pass type II membrane protein {ECO:0000255}. Secreted {ECO:0000269|PubMed:32827291}. |
| Mouse PG classification | NA |
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