| Gene Information | |
|---|---|
| Gene Name | PHLDA3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 127 |
| Protein Names | Pleckstrin homology-like domain family A member 3 (TDAG51/Ipl homolog 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000174307 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9Y5J5 |
| Gene Card | PHLDA3 |
| Uniprot ID | Q9Y5J5 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.081297761) |
| Ortholog in Animals | Alpaca_ PHLDA3 ( ortholog_one2one ) Dog_ PHLDA3 ( ortholog_one2one ) GuineaPig_ PHLDA3 ( ortholog_one2one ) Macaque_ PHLDA3 ( ortholog_one2one ) Mouse_ Phlda3 ( ortholog_one2one ) Pig_ PHLDA3 ( ortholog_one2one ) Rat_ Phlda3 ( ortholog_one2one ) Rabbit_ PHLDA3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PHLDA2, PHLDA1 |
| Tissue | NA |
| Tissue Specificity | Widely expressed with lowest expression in liver and spleen. {ECO:0000269|PubMed:10594239}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35383942 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:19203586}. Membrane {ECO:0000269|PubMed:19203586}; Peripheral membrane protein {ECO:0000269|PubMed:19203586}. |
| Mouse PG classification | NA |
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