| Gene Information | |
|---|---|
| Gene Name | KIAA0981 |
| Organism | Homo sapiens (Human) |
| Gene Length | 2098 |
| Protein Names | 1-phosphatidylinositol 3-phosphate 5-kinase (Phosphatidylinositol 3-phosphate 5-kinase) (EC 2.7.1.150) (FYVE finger-containing phosphoinositide kinase) (PIKfyve) (Phosphatidylinositol 3-phosphate 5-kinase type III) (PIPkin-III) (Type III PIP kinase) (Serine-protein kinase PIKFYVE) (EC 2.7.11.1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9Y2I7 |
| Gene Card | PIKFYVE |
| Uniprot ID | Q9Y2I7 |
| Pfam | PF00118; PF00610; PF01363; PF01504 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.073333(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7K2V (EM 6.60A ) |
| DBSNP | rs16840913 rs10932258 rs2363468 rs893254 rs893253 rs999890 rs121918336 rs1529979 rs2289170 |
| Subcellular location [CC] | Endosome membrane {ECO:0000269|PubMed:11706043, ECO:0000269|PubMed:17556371}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9Z1T6}. Early endosome membrane {ECO:0000269|PubMed:30612035}; Peripheral membrane protein. Cytoplasmic vesicle, phagosome membrane {ECO:0000269|PubMed:30612035}; Peripheral membrane protein {ECO:0000305}. Late endosome membrane {ECO:0000269|PubMed:11706043}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9Z1T6}. Note=Mainly associated with membranes of the late endocytic pathway. {ECO:0000269|PubMed:11706043}. |
| Mouse PG classification | NA |
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