| Gene Information | |
|---|---|
| Gene Name | IFI27 |
| Organism | Homo sapiens (Human) |
| Gene Length | 122 |
| Protein Names | Interferon alpha-inducible protein 27, mitochondrial (p27) (Interferon alpha-induced 11.5 kDa protein) (Interferon-stimulated gene 12a protein) (ISG12(a)) (ISG12A) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 55 ( ENSG00000165949 ) 3 ( ENSG00000275214 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | P40305 |
| Gene Card | IFI27 |
| Uniprot ID | P40305 |
| Pfam | PF06140 |
| In ASD | no |
| Allosteric Prediction | no (-0.389034205) |
| Ortholog in Animals | Alpaca_ IFI27 ( ortholog_one2one ) Macaque_ IFI27 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | IFI6, IFI27L2, IFI27L1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2227974 |
| Subcellular location [CC] | Mitochondrion membrane {ECO:0000269|PubMed:18330707, ECO:0000269|PubMed:27673746}; Multi-pass membrane protein {ECO:0000255}. Nucleus inner membrane {ECO:0000269|PubMed:11722583, ECO:0000269|PubMed:22427340}; Multi-pass membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:22427340}; Multi-pass membrane protein {ECO:0000255}. Note=Exclusive localizations in either the nucleus or the mitochondrion have been reported. {ECO:0000269|PubMed:22427340, ECO:0000269|PubMed:27673746}. |
| Mouse PG classification | NA |
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