| Gene Information | |
|---|---|
| Gene Name | FRMD4B |
| Organism | Homo sapiens (Human) |
| Gene Length | 1034 |
| Protein Names | FERM domain-containing protein 4B (GRP1-binding protein GRSP1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000114541 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q9Y2L6 |
| Gene Card | FRMD4B |
| Uniprot ID | Q9Y2L6 |
| Pfam | PF11819; PF09380; PF00373; PF09379 |
| In ASD | no |
| Allosteric Prediction | no (-1.288419796) |
| Ortholog in Animals | Alpaca_ FRMD4B ( ortholog_one2one ) Dog_ FRMD4B ( ortholog_one2one ) GuineaPig_ FRMD4B ( ortholog_one2one ) Macaque_ FRMD4B ( ortholog_one2one ) Mouse_ Frmd4b ( ortholog_one2one ) Pig_ FRMD4B ( ortholog_one2one ) Rat_ Frmd4b ( ortholog_one2one ) Rabbit_ FRMD4B ( ortholog_one2one ) |
| Ohnologs | FRMD4A |
| Paralogs | FRMD4A, NF2, ERMN, MSN, EZR, RDX |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q920B0}. Cell junction, tight junction {ECO:0000250|UniProtKB:Q920B0}. Cell junction, adherens junction {ECO:0000250|UniProtKB:Q920B0}. Note=Colocalized with PARD3 at adherens junction and tight junction. {ECO:0000250|UniProtKB:Q920B0}. |
| Mouse PG classification | NA |
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