| Gene Information | |
|---|---|
| Gene Name | FKBP6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 327 |
| Protein Names | Inactive peptidyl-prolyl cis-trans isomerase FKBP6 (Inactive PPIase FKBP6) (36 kDa FK506-binding protein) (36 kDa FKBP) (FKBP-36) (FK506-binding protein 6) (FKBP-6) (Immunophilin FKBP36) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000077800 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O75344 |
| Gene Card | FKBP6 |
| Uniprot ID | O75344 |
| Pfam | PF00254 |
| In ASD | no |
| Allosteric Prediction | no (-0.498510898) |
| Ortholog in Animals | Alpaca_ FKBP6 ( ortholog_one2many ) Dog_ FKBP6 ( ortholog_one2one ) Macaque_ FKBP6 ( ortholog_one2one ) Mouse_ Fkbp6 ( ortholog_one2one ) Pig_ FKBP6 ( ortholog_one2one ) Rat_ Fkbp6 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | FKBP11, FKBP14, FKBP3, TTC9, FKBP10, FKBP1A, FKBP1C, FKBP1B, FKBP7, FKBP2, FKBP8, TTC9B, TTC9C, FKBPL, FKBP5, FKBP4, FKBP15, FKBP9 |
| Tissue | testis |
| Tissue Specificity | Detected in all tissues examined, with higher expression in testis, heart, skeletal muscle, liver, and kidney. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.0125(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 3B7X (X-ray 2.10A ) |
| DBSNP | rs147213094 |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000250}. Nucleus {ECO:0000250}. Chromosome {ECO:0000250}. Note=Does not localize to pi-bodies. Localizes to meiotic chromosome cores and regions of homologous chromosome synapsis (By similarity). {ECO:0000250}. |
| Mouse PG classification | NA |
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