| Gene Information | |
|---|---|
| Gene Name | NENF |
| Organism | Homo sapiens (Human) |
| Gene Length | 172 |
| Protein Names | Neudesin (Cell immortalization-related protein 2) (Neuron-derived neurotrophic factor) (Protein GIG47) (Secreted protein of unknown function) (SPUF protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000117691 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9UMX5 |
| Gene Card | NENF |
| Uniprot ID | Q9UMX5 |
| Pfam | PF00173 |
| In ASD | no |
| Allosteric Prediction | no (-0.594826558) |
| Ortholog in Animals | Alpaca_ NENF ( ortholog_one2one ) Dog_ NENF ( ortholog_one2one ) Macaque_ NENF ( ortholog_one2one ) Mouse_ Nenf ( ortholog_one2one ) Pig_ NENF ( ortholog_one2one ) Rat_ Nenf ( ortholog_one2one ) Rabbit_ NENF ( ortholog_one2one ) |
| Ohnologs | PGRMC2 |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed with high expression in heart. Over-expressed in various tumors including carcinomas of the uterine cervix, lymphoma, colon, lung, skin and leukemia, as well as carcinoma of the breast. {ECO:0000269|PubMed:22748190}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Secreted, extracellular space {ECO:0000269|PubMed:31536960}. Mitochondrion {ECO:0000269|PubMed:31536960}. Endoplasmic reticulum {ECO:0000269|PubMed:31536960}. Note=Localized to mitochondria and endoplasmic reticulum by PINK1 and PARK7. {ECO:0000269|PubMed:31536960}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |