Gene Information
Gene NamePOLR3B
OrganismHomo sapiens (Human)
Gene Length1133
Protein NamesDNA-directed RNA polymerase III subunit RPC2 (RNA polymerase III subunit C2) (EC 2.7.7.6) (C128) (DNA-directed RNA polymerase III 127.6 kDa polypeptide) (DNA-directed RNA polymerase III subunit B)
Target NameNA
Target TypeNA
Gene Age>4290 ( ENSG00000013503 )
Evolutionary StageCellular_organisms
AlphaFoldDBQ9NW08
Gene CardPOLR3B
Uniprot IDQ9NW08
PfamPF04563; PF04561; PF04565; PF04566; PF04567; PF00562; PF04560
In ASDno
Allosteric Predictionno (-0.184204475)
Ortholog in AnimalsAlpaca_ POLR3B ( ortholog_one2one )
Dog_ POLR3B ( ortholog_one2one )
GuineaPig_ POLR3B ( ortholog_one2one )
Macaque_ POLR3B ( ortholog_one2one )
Mouse_ Polr3b ( ortholog_one2one )
Pig_ POLR3B ( ortholog_one2one )
Rat_ Polr3b ( ortholog_one2one )
Rabbit_ POLR3B ( ortholog_one2one )
OhnologsNA
ParalogsPOLR2B, POLR1B
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.345873(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 7A6H  (EM  3.30A  )  7AE1  (EM  2.80A  )  7AE3  (EM  3.10A  )  7AEA  (EM  3.40A  )  7AST  (EM  4.00A  )  7D58  (EM  2.90A  )  7D59  (EM  3.10A  )  7DN3  (EM  3.50A  )  7DU2  (EM  3.35A  )  7FJI  (EM  3.60A  )  7FJJ  (EM  3.60A  ) 
DBSNP rs1442212683  rs267608683  rs138249161  rs17038460  rs267608687  rs267608689 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:33417887}.
Mouse PG classificationNA
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