| Gene Information | |
|---|---|
| Gene Name | LPAR4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 370 |
| Protein Names | Lysophosphatidic acid receptor 4 (LPA receptor 4) (LPA-4) (G-protein coupled receptor 23) (P2Y purinoceptor 9) (P2Y9) (P2Y5-like receptor) (Purinergic receptor 9) |
| Target Name | lysophosphatidic acid receptor 4 |
| Target Type | Literature-reported target |
| Gene Age | 645 ( ENSG00000147145 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q99677 |
| Gene Card | LPAR4 |
| Uniprot ID | Q99677 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | yes (0.619823796) |
| Ortholog in Animals | Alpaca_ LPAR4 ( ortholog_one2one ) Dog_ LPAR4 ( ortholog_one2one ) Macaque_ LPAR4 ( ortholog_one2one ) Mouse_ Lpar4 ( ortholog_one2one ) Pig_ LPAR4 ( ortholog_one2one ) Rat_ Lpar4 ( ortholog_one2one ) |
| Ohnologs | LPAR6, CXCR1, CXCR2, CCR4 |
| Paralogs | F2RL2, P2RY8, F2RL1, F2R, F2RL3, GPR18, GPR65, CYSLTR2, GPR17, GPR4, CYSLTR1, GPR20, LPAR6, P2RY10, GPR35, GPR55 |
| Tissue | NA |
| Tissue Specificity | High expression in ovary. Not detected in the brain regions thalamus, putamen, caudate, frontal cortex, pons, hypothalamus and hippocampus. {ECO:0000269|PubMed:12724320}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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