| Gene Information | |
|---|---|
| Gene Name | KIAA0799 |
| Organism | Homo sapiens (Human) |
| Gene Length | 2058 |
| Protein Names | Unconventional myosin-X (Unconventional myosin-10) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9HD67 |
| Gene Card | MYO10 |
| Uniprot ID | Q9HD67 |
| Pfam | PF00373; PF00612; PF16735; PF00063; PF00784; PF00169; PF00788; PF18597 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:10984435}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);0.003990(Rat);0.026667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2LW9 (NMR - ) 3AU4 (X-ray 1.90A ) 3AU5 (X-ray 2.55A ) 3PZD (X-ray 2.50A ) 5I0H (X-ray 1.80A ) 5I0I (X-ray 3.15A ) 5KG8 (EM 9.10A ) |
| DBSNP | rs17707947 rs7737765 rs6870170 rs11750538 rs26740 rs25901 |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000269|PubMed:10984435}. Cell projection, lamellipodium {ECO:0000269|PubMed:10984435}. Cell projection, ruffle {ECO:0000269|PubMed:10984435}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:10984435}. Cell projection, filopodium tip {ECO:0000269|PubMed:10984435}. Cytoplasm, cell cortex {ECO:0000269|PubMed:10984435}. Cell projection, filopodium membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=May be in an inactive, monomeric conformation in the cytosol. Detected in cytoplasmic punctae and in cell projections. Colocalizes with actin fibers. Undergoes forward and rearward movements within filopodia. Interacts with microtubules. |
| Mouse PG classification | NA |
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