| Gene Information | |
|---|---|
| Gene Name | GBP5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 586 |
| Protein Names | Guanylate-binding protein 5 (EC 3.6.5.-) (GBP-TA antigen) (GTP-binding protein 5) (GBP-5) (Guanine nucleotide-binding protein 5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 132 ( ENSG00000154451 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q96PP8 |
| Gene Card | GBP5 |
| Uniprot ID | Q96PP8 |
| Pfam | PF02263; PF02841 |
| In ASD | no |
| Allosteric Prediction | no (-0.332524984) |
| Ortholog in Animals | Alpaca_ GBP5 ( ortholog_one2one ) Mouse_ Gbp5 ( ortholog_one2one ) Pig_ GBP5 ( ortholog_one2one ) Rat_ Gbp5 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ATL1, ATL2, GBP7, ATL3, GBP2, GBP6, GBP1, RNF112, GBP4, GBP3 |
| Tissue | NA |
| Tissue Specificity | Expressed in peripheral blood monocytes (at protein level). {ECO:0000269|PubMed:15175044}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7CKF (X-ray 2.28A ) 7E59 (X-ray 3.00A ) 7E5A (X-ray 2.50A ) |
| DBSNP | rs17130763 rs3806339 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:17266443, ECO:0000269|PubMed:21151871}. Golgi apparatus membrane {ECO:0000269|PubMed:17266443, ECO:0000269|PubMed:21151871}; Lipid-anchor {ECO:0000269|PubMed:21151871}. Cytoplasmic vesicle {ECO:0000250|UniProtKB:Q8CFB4}. |
| Mouse PG classification | NA |
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