| Gene Information | |
|---|---|
| Gene Name | A4GALT |
| Organism | Homo sapiens (Human) |
| Gene Length | 353 |
| Protein Names | Lactosylceramide 4-alpha-galactosyltransferase (EC 2.4.1.228) (Alpha-1,4-N-acetylglucosaminyltransferase) (Alpha-1,4-galactosyltransferase) (Alpha4Gal-T1) (CD77 synthase) (Globotriaosylceramide synthase) (Gb3 synthase) (P1/Pk synthase) (UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 424 ( ENSG00000128274 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9NPC4 |
| Gene Card | A4GALT |
| Uniprot ID | Q9NPC4 |
| Pfam | PF04572; PF04488 |
| In ASD | no |
| Allosteric Prediction | no (-0.846411008) |
| Ortholog in Animals | Alpaca_ A4GALT ( ortholog_one2one ) Dog_ A4GALT ( ortholog_one2one ) GuineaPig_ A4GALT ( ortholog_one2one ) Macaque_ A4GALT ( ortholog_one2one ) Mouse_ A4galt ( ortholog_one2one ) Pig_ A4GALT ( ortholog_one2one ) Rat_ A4galt ( ortholog_one2one ) Rabbit_ A4GALT ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | A4GNT |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Highly expressed in kidney, heart, spleen, liver, testis and placenta. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11541159 rs28915383 rs74315453 rs28940572 rs397514502 rs28940571 |
| Subcellular location [CC] | Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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