| Gene Information | |
|---|---|
| Gene Name | MSL3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 521 |
| Protein Names | Male-specific lethal 3 homolog (Male-specific lethal-3 homolog 1) (Male-specific lethal-3 protein-like 1) (MSL3-like 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000005302 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8N5Y2 |
| Gene Card | MSL3 |
| Uniprot ID | Q8N5Y2 |
| Pfam | PF05712; PF11717 |
| In ASD | no |
| Allosteric Prediction | no (-0.161407572) |
| Ortholog in Animals | Alpaca_ MSL3 ( ortholog_one2one ) Dog_ MSL3 ( ortholog_one2one ) GuineaPig_ MSL3 ( ortholog_one2one ) Macaque_ MSL3 ( ortholog_one2one ) Mouse_ Msl3 ( ortholog_one2many ) Mouse_ Msl3l2 ( ortholog_one2many ) Pig_ MSL3 ( ortholog_one2one ) Rat_ Msl3l2 ( ortholog_one2many ) Rat_ Msl3 ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | MORF4L1, MORF4L2 |
| Tissue | NA |
| Tissue Specificity | Expressed in many tissues including liver, pancreas, heart, lung, kidney, skeletal muscle, brain, and placenta, with highest expression in skeletal muscle and heart. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2Y0N (X-ray 3.00A ) 3OA6 (X-ray 2.35A ) 3OB9 (X-ray 2.50A ) |
| DBSNP | rs150938844 rs1051595 rs1555906707 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:30224647}. |
| Mouse PG classification | NA |
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